Extracting Biochemical Reaction Kinetics from Time Series Data

نویسندگان

  • Edmund J. Crampin
  • Patrick E. McSharry
  • Santiago Schnell
چکیده

We consider the problem of inferring kinetic mechanisms for biochemical reactions from time series data. Using a priori knowledge about the structure of chemical reaction kinetics we develop global nonlinear models which use elementary reactions as a basis set, and discuss model construction using top-down and bottom-up approaches.

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تاریخ انتشار 2004